Description

Methyl 1-(Pyridin-4-Yl)Cyclopropanecarboxylate CAS NO 1354940-74-1 is a high-purity, synthetically valuable organic compound featuring a cyclopropane ring fused with a pyridine moiety. This unique heterocyclic structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients. The compound's defined stereochemistry and functional groups enable precise molecular modifications essential for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and anti-infective therapeutics.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and functional polymers due to its conjugated system.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and GMP production.

Basic Information

Product Name	Methyl 1-(Pyridin-4-Yl)Cyclopropanecarboxylate
CAS No.	1354940-74-1
Molecular Formula	C10H11NO2
Molecular Weight	177.20 g/mol
Synonyms	Methyl 1-(4-pyridyl)cyclopropanecarboxylate; 1-(Pyridin-4-yl)cyclopropanecarboxylic acid methyl ester; 4-Pyridinecyclopropanecarboxylic acid, methyl ester; Cyclopropanecarboxylic acid, 1-(4-pyridinyl)-, methyl ester; Methyl 1-(4-pyridinyl)cyclopropanecarboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 1-(Pyridin-4-Yl)Cyclopropanecarboxylate adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your critical synthesis work. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment. We support development from research to commercial scale with appropriate documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider maintaining the material under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.