Description

1,2,3,4-Tetrahydro-2,7-Naphthyridine Hydrochloride is a high-purity organic salt compound that serves as a critical pharmaceutical intermediate and versatile building block in medicinal chemistry. Its value lies in its fused bicyclic heterocyclic structure, which is a privileged scaffold for designing bioactive molecules targeting a range of therapeutic areas. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to synthesize novel compounds for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in early-stage drug discovery.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel active ingredients for crop protection.
• Chemical Biology Probes: Utilized in the development of tool compounds and molecular probes for studying biological pathways.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for specialized, high-value chemical products.

Basic Information

Product Name	1,2,3,4-Tetrahydro-2,7-Naphthyridine Hydrochloride
CAS No.	1354940-72-9
Molecular Formula	C8H11ClN2
Molecular Weight	170.64 g/mol
Synonyms	2,7-Naphthyridine, 1,2,3,4-tetrahydro-, hydrochloride; 1,2,3,4-Tetrahydro-2,7-naphthyridine HCl; 2,7-Naphthyridine, 1,2,3,4-tetrahydro-, monohydrochloride; THN Hydrochloride; 1,2,3,4-Tetrahydro-2,7-diazanaphthalene hydrochloride
EINECS	Contact for details

Quality Control

Our 1,2,3,4-Tetrahydro-2,7-Naphthyridine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing key parameters such as assay, impurity profile, and residual solvents. Our quality commitment supports applications requiring high standards, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.