Description

Methyl (2S,4S)-4-(2-Furoyloxy)-2-Pyrrolidinecarboxylate Hydrochloride is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Asymmetric Synthesis: Utilized in catalytic and stoichiometric asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Protease Inhibitor Research: Serves as a precursor or core structure in the development of protease inhibitors for antiviral and anticancer therapies.
• Agrochemical Synthesis: Employed in the research and production of advanced, enantiomerically pure agrochemicals.
• Academic & Process Chemistry: Used in academic research for methodological studies and in process chemistry for route scouting and optimization.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract manufacturing organizations (CMOs) serving the life sciences sector.

Basic Information

Product Name	Methyl (2S,4S)-4-(2-Furoyloxy)-2-Pyrrolidinecarboxylate Hydrochloride
CAS No.	1354487-17-4
Molecular Formula	C11H14ClNO5
Molecular Weight	275.69 g/mol
Synonyms	Methyl (2S,4S)-4-[(furan-2-carbonyl)oxy]pyrrolidine-2-carboxylate hydrochloride; (2S,4S)-Methyl 4-(2-furoyloxy)pyrrolidine-2-carboxylate hydrochloride; (2S,4S)-4-(2-Furoyloxy)-2-pyrrolidinecarboxylic acid methyl ester hydrochloride; L-Proline, 4-[(2-furanylcarbonyl)oxy]-, methyl ester, hydrochloride, (2S,4S)-; Methyl 4-(furan-2-carbonyloxy)-L-prolinate hydrochloride; (2S,4S)-Methyl 4-(furan-2-carbonyloxy)pyrrolidine-2-carboxylate HCl
EINECS	Contact for details

Quality Control

Our Methyl (2S,4S)-4-(2-Furoyloxy)-2-Pyrrolidinecarboxylate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting standards for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment and allowed to reach room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.