Description

[1-((E)-4-Phenyl-But-3-Enyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate designed for complex organic synthesis. This compound is critical for research and development in medicinal chemistry, offering a versatile piperidine-based scaffold for constructing novel active molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its functionalized piperidine core.
• Custom Synthesis: Serves as a starting material or intermediate for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial production scales.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying biological pathways and target validation.

Basic Information

Product Name	[1-((E)-4-Phenyl-But-3-Enyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester
CAS No.	1353990-99-4
Molecular Formula	C20H30N2O2
Molecular Weight	330.47 g/mol
Synonyms	tert-Butyl N-[1-[(E)-4-phenylbut-3-en-1-yl]-4-piperidinyl]carbamate; 1-[(1E)-4-Phenyl-1-buten-1-yl]-4-piperidinylcarbamic Acid 1,1-Dimethylethyl Ester; BOC-Piperidine Intermediate; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]-1-[(1E)-4-phenyl-1-buten-1-yl]piperidine; (1-((E)-4-Phenylbut-3-en-1-yl)piperidin-4-yl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our [1-((E)-4-Phenyl-But-3-Enyl)-Piperidin-4-Yl]-Carbamic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical quality attributes. We adhere to cGMP principles for pharmaceutical intermediates to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.