Description

4-[(Methyl-Piperidin-3-Yl-Amino)-Methyl]-Benzonitrile Hydrochloride is a high-purity, advanced pharmaceutical intermediate featuring a benzonitrile core functionalized with a methyl-piperidinylamino moiety. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel small molecule therapeutics targeting central nervous system and other disorders. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the multi-step synthesis of complex therapeutic molecules.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for exploratory organic synthesis and pharmacological studies.

Basic Information

Product Name	4-[(Methyl-Piperidin-3-Yl-Amino)-Methyl]-Benzonitrile Hydrochloride
CAS No.	1353989-72-6
Molecular Formula	C15H21N3·HCl
Molecular Weight	279.81 g/mol (Free base: 243.35 g/mol)
Synonyms	4-[(Methyl(piperidin-3-yl)amino)methyl]benzonitrile hydrochloride; 4-((Methyl(3-piperidinyl)amino)methyl)benzonitrile HCl; 4-[(Methyl-piperidin-3-yl-amino)-methyl]-benzonitril hydrochloride; 1353989-72-6; Benzonitrile, 4-[[methyl(3-piperidinyl)amino]methyl]-, hydrochloride; 4-((Methyl(piperidin-3-yl)amino)methyl)benzonitrile hydrochloride
EINECS	Contact for details

Quality Control

Our 4-[(Methyl-Piperidin-3-Yl-Amino)-Methyl]-Benzonitrile Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Assay (Titration)	97.0% - 103.0% (on anhydrous basis)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.