Description

1-(Pyridine-2-Sulfonyl)-Piperidin-3-Ol is a high-purity, advanced pharmaceutical intermediate characterized by its unique sulfonyl-piperidine-pyridine hybrid structure. This compound is of significant commercial interest for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for central nervous system (CNS) and anti-infective agents. The material is supplied under strict quality control to ensure batch-to-batch consistency for critical synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• API Development: Used in the process research and development (PR&D) and scale-up phases for new chemical entities (NCEs).
• Biochemical Tool Compound: May be employed in biochemical assays as a probe or inhibitor to study specific enzyme or receptor functions.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for clients.

Basic Information

Item	Details
Product Name	1-(Pyridine-2-Sulfonyl)-Piperidin-3-Ol
CAS No.	1353986-28-3
Molecular Formula	C10H14N2O3S
Molecular Weight	242.30 g/mol
Synonyms	3-Piperidinol, 1-(2-pyridinylsulfonyl)-; 1-(Pyridin-2-ylsulfonyl)piperidin-3-ol; 1-(Pyridine-2-sulfonyl)piperidin-3-ol; Piperidin-3-ol, 1-(pyridine-2-sulfonyl)-; 1353986-28-3; 1-(2-Pyridylsulfonyl)-3-hydroxypiperidine
EINECS	Contact for details

Quality Control

Our 1-(Pyridine-2-Sulfonyl)-Piperidin-3-Ol is manufactured under a quality management system in compliance with cGMP guidelines for advanced intermediates. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR/LC-MS for structural confirmation, to ensure it meets stringent specifications for pharmaceutical R&D use. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.