Description

2-(Pyridin-2-Ylsulfanylmethyl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic scaffold. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for constructing complex molecules with potential biological activity. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its modifiable pyrrolidine and pyridine motifs.
• Process Chemistry Development: Serves as a starting material or intermediate in the scale-up and route scouting for active pharmaceutical ingredient (API) manufacturing.
• Agrochemical Synthesis: Intermediate in the research and development of new pesticides and herbicides, leveraging its heterocyclic structure.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying enzyme function or protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	2-(Pyridin-2-Ylsulfanylmethyl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	1353967-38-0
Molecular Formula	C16H24N2O2S
Molecular Weight	308.44 g/mol
Synonyms	tert-Butyl 2-[(pyridin-2-ylsulfanyl)methyl]pyrrolidine-1-carboxylate; 1-Boc-2-((pyridin-2-ylthio)methyl)pyrrolidine; 2-((Pyridin-2-ylthio)methyl)pyrrolidine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-2-((2-pyridylthio)methyl)pyrrolidine; N-Boc-2-((pyridin-2-ylthio)methyl)pyrrolidine; Pyrrolidine-1-carboxylic acid, 2-[(2-pyridinylthio)methyl]-, 1,1-dimethylethyl ester; 1353967-38-0; Boc-2-((Pyridin-2-ylthio)methyl)pyrrolidine
EINECS	Contact for details

Quality Control

Our 2-(Pyridin-2-Ylsulfanylmethyl)-Pyrrolidine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development and commercial projects requiring compliance with cGMP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.