Description

n-[3-(Pyrrolidin-1-Yl)Propyl]-5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a sophisticated boronic ester derivative that serves as a critical intermediate in modern synthetic chemistry. Its value lies in its dual functionality, combining a protected boronic acid group with a pyridyl amine moiety, enabling precise cross-coupling and functionalization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors developing novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a versatile boronic ester reagent for forming carbon-carbon bonds in complex molecule assembly.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Intermediate for creating functionalized polymers, ligands for catalysts, and organic electronic materials.
• Chemical Biology & Proteomics: Serves as a probe or linker in the development of biochemical tools and affinity purification tags.
• Academic & R&D Laboratories: Fundamental reagent for methodological development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	n-[3-(Pyrrolidin-1-Yl)Propyl]-5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1353880-12-2
Molecular Formula	C18H30BN3O2
Molecular Weight	331.27 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-[3-(1-pyrrolidinyl)propyl]-2-pyridinamine; 2-Pyridinamine, 5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-[3-(1-pyrrolidinyl)propyl]-; N-[3-(Pyrrolidin-1-yl)propyl]-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; 1353880-12-2; 5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(3-(pyrrolidin-1-yl)propyl)pyridin-2-amine; Boronic ester pyridylamine derivative
EINECS	Contact for details

Quality Control

Our n-[3-(Pyrrolidin-1-Yl)Propyl]-5-(Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.