Description

tert-Butyl 2-Chloro-4-Methylpyridin-3-Ylcarbamate is a high-purity, advanced pharmaceutical intermediate characterized by its specific pyridine and carbamate functional groups. This compound is of significant value in modern organic synthesis, serving as a critical building block for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, amide formations, and other transformations to introduce functionalized pyridine motifs.
• Material Science: Potential monomer or additive in the research of specialty polymers and advanced materials.
• Academic & R&D: Serves as a standard or starting material in medicinal chemistry and process development laboratories.

Basic Information

Product Name	tert-Butyl 2-Chloro-4-Methylpyridin-3-Ylcarbamate
CAS No.	1353677-48-1
Molecular Formula	C12H17ClN2O2
Molecular Weight	256.73 g/mol
Synonyms	3-((tert-Butoxycarbonyl)amino)-2-chloro-4-methylpyridine; 2-Chloro-4-methylpyridin-3-yl-carbamic acid tert-butyl ester; tert-Butyl N-(2-chloro-4-methyl-3-pyridinyl)carbamate; 2-Chloro-4-methyl-3-pyridinylcarbamic acid 1,1-dimethylethyl ester; BOC-2-Chloro-4-methyl-3-aminopyridine; tert-Butyl (2-chloro-4-methylpyridin-3-yl)carbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Chloro-4-Methylpyridin-3-Ylcarbamate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.