Description

6-Chloro-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazolo[4,3-C]Pyridine is a high-value, heterocyclic organic building block of significant interest in advanced chemical synthesis. Its core value lies in its role as a key protected intermediate for the development of novel pharmaceutical compounds, particularly kinase inhibitors. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require sophisticated scaffolds for drug discovery programs.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for targeted cancer therapies and kinase inhibitors.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Used in the research and synthesis of novel crop protection agents and pesticides.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Fine Chemical Synthesis: Acts as a specialized building block for creating complex molecules in custom synthesis and contract manufacturing.

Basic Information

Product Name	6-Chloro-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazolo[4,3-C]Pyridine
CAS No.	1353637-44-1
Molecular Formula	C11H12ClN3O
Molecular Weight	237.69 g/mol
Synonyms	6-Chloro-1-(tetrahydro-2H-pyran-2-yl)-1H-pyrazolo[4,3-c]pyridine; 1-(Oxan-2-yl)-6-chloro-1H-pyrazolo[4,3-c]pyridine; 6-Chloro-1-(tetrahydropyran-2-yl)-1H-pyrazolo[4,3-c]pyridine; 6-Chloro-1-(THP)-1H-pyrazolo[4,3-c]pyridine; THP-protected 6-chloropyrazolopyridine; Pyrazolo[4,3-c]pyridine, 6-chloro-1-(tetrahydro-2H-pyran-2-yl)-; CAS 1353637-44-1
EINECS	Contact for details

Quality Control

Our 6-Chloro-1-(Tetrahydro-2H-Pyran-2-Yl)-1H-Pyrazolo[4,3-C]Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.