Description

5,6,7,8-Tetrahydro-1,6-Naphthyridin-3-Amine Hydrochloride is a high-purity organic salt of significant interest in advanced chemical synthesis. This compound serves as a critical pharmaceutical intermediate and versatile building block for the development of novel active ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors seeking to develop new therapeutic agents and specialty molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Chemical Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Agrochemical Research: Serves as a core structure for developing new crop protection agents and pesticides.
• Academic & Contract Research: Employed in university and CRO laboratories for exploratory synthetic chemistry and methodological studies.
• Fine Chemical Synthesis: Integral for creating complex, high-value specialty chemicals and functional materials.
• Bioconjugate Chemistry: Potential use in the development of antibody-drug conjugates (ADCs) and other targeted therapies.

Basic Information

Product Name	5,6,7,8-Tetrahydro-1,6-Naphthyridin-3-Amine Hydrochloride
CAS No.	1353101-01-5
Molecular Formula	C8H12ClN3
Molecular Weight	185.65 g/mol
Synonyms	3-Amino-5,6,7,8-tetrahydro-1,6-naphthyridine hydrochloride; 1,6-Naphthyridine, 3-amino-5,6,7,8-tetrahydro-, hydrochloride; 5,6,7,8-Tetrahydro[1,6]naphthyridin-3-ylamine hydrochloride; THN-3-Amine HCl; 3-Amino-5,6,7,8-tetrahydro-1,6-naphthyridine HCl; 1353101-01-5; 3-Amino-THN hydrochloride
EINECS	Contact for details

Quality Control

Our 5,6,7,8-Tetrahydro-1,6-Naphthyridin-3-Amine Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the stringent requirements of pharmaceutical intermediate production and research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the original container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.