Description

(R)-2,2',3,3'-Tetrahydro-6,6'-Bis(4-Nitrophenyl)-1,1'-Spirobi[1H-Indene]-7,7'-Diol is a high-value, chiral spirobiindane derivative of significant interest in advanced organic synthesis. This compound serves as a sophisticated ligand precursor or chiral building block for the development of asymmetric catalysts and functional materials. It is primarily required by R&D and process chemistry teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel, optically active molecules.

Application

• Asymmetric Catalysis: As a key chiral ligand or scaffold for constructing novel metal-complex catalysts used in enantioselective synthesis.
• Pharmaceutical Intermediates: In the research and development of active pharmaceutical ingredients (APIs) requiring high stereochemical purity.
• Advanced Material Science: As a building block for chiral polymers, liquid crystals, or molecular devices where the rigid spiro structure imparts specific properties.
• Agrochemical Synthesis: For the development of new, enantiomerically pure herbicides, fungicides, or plant growth regulators.
• Academic & Industrial Research: As a reference standard or starting material in methodological studies for new C-C bond formation or functionalization reactions.
• Chiral Stationary Phases (CSPs): Potential use in the development of high-performance liquid chromatography (HPLC) columns for enantiomer separation.

Basic Information

Product Name	(R)-2,2',3,3'-Tetrahydro-6,6'-Bis(4-Nitrophenyl)-1,1'-Spirobi[1H-Indene]-7,7'-Diol
CAS No.	1352810-33-3
Molecular Formula	C33H24N2O6
Molecular Weight	544.56 g/mol
Synonyms	(R)-6,6'-Bis(4-nitrophenyl)-1,1'-spirobi[1H-indene]-7,7'-diol; (R)-2,2',3,3'-Tetrahydro-6,6'-bis(4-nitrophenyl)-1,1'-spirobi[indene]-7,7'-diol; (R)-SPINOL Nitro Derivative; (R)-2,2',3,3'-Tetrahydro-1,1'-spirobi[1H-indene]-7,7'-diol, 6,6'-bis(4-nitrophenyl)-, (R)-; Chiral Spirobiindane Nitro Compound; (R)-6,6'-Di(4-nitrophenyl)SPINOL; (R)-7,7'-Dihydroxy-6,6'-bis(4-nitrophenyl)-1,1'-spirobi[indane]
EINECS	Contact for details

Quality Control

Our production of (R)-2,2',3,3'-Tetrahydro-6,6'-Bis(4-Nitrophenyl)-1,1'-Spirobi[1H-Indene]-7,7'-Diol adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high chiral purity. Each lot is characterized using advanced analytical techniques including HPLC, chiral HPLC, 1H/13C NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to strong light should be avoided. Keep container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.