Description

1-Thia-6-Aza-Spiro[3.3]Heptane-1,1-Dioxide is a high-value, heterocyclic building block featuring a unique spirocyclic sulfonamide scaffold. This compound is critical for medicinal chemistry research and development, enabling the rapid exploration of novel chemical space in drug discovery programs. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the synthesis of innovative therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing novel small molecule drug candidates, particularly in CNS and oncology research.
• Medicinal Chemistry Scaffold: Used to introduce constrained, three-dimensional spirocyclic and sulfonamide motifs into lead compounds to optimize potency, selectivity, and physicochemical properties.
• Chemical Biology Probe Synthesis: Serves as a core structure for developing tool compounds to study biological targets and pathways.
• Library Synthesis for High-Throughput Screening: Enables the generation of diverse compound libraries for hit identification in early-stage drug discovery.
• Agrochemical Research: Potential intermediate in the development of new active ingredients with novel modes of action.
• Material Science Exploration: Investigated as a monomer or precursor for specialty polymers with unique thermal or mechanical properties.

Basic Information

Product Name	1-Thia-6-Aza-Spiro[3.3]Heptane-1,1-Dioxide
CAS No.	1352546-75-8
Molecular Formula	C5H9NO2S
Molecular Weight	147.20 g/mol
Synonyms	1-Thia-6-azaspiro[3.3]heptane 1,1-dioxide; 6-Aza-1-thiaspiro[3.3]heptane 1,1-dioxide; 1,1-Dioxo-1-thia-6-azaspiro[3.3]heptane; 1-Thia-6-aza-spiro[3.3]heptane-1,1-dioxide; Spiro[3.3]heptane-6-amine, 1-thia-, 1,1-dioxide; Sulfamoylcyclopropylmethane; (Aminosulfonyl)cyclopropylmethane
EINECS	Contact for details

Quality Control

Our 1-Thia-6-Aza-Spiro[3.3]Heptane-1,1-Dioxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.