Description

5-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is of significant commercial importance for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and antiviral research. It is primarily sought after by R&D laboratories, custom synthesis providers, and large-scale pharmaceutical manufacturers engaged in the development of next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially those targeting specific kinase inhibitors and other biological pathways.
• Organic Synthesis Building Block: Used in medicinal chemistry for the construction of imidazopyridine-based scaffolds with potential biological activity.
• Research & Development (R&D): Essential for academic and industrial research programs focused on developing new chemical entities (NCEs) and exploring structure-activity relationships (SAR).
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations for use in the cGMP production of clinical trial materials and commercial APIs.
• Agrochemical Research: Potential application as an intermediate in the development of new agrochemicals and plant protection agents.
• Material Science: Investigated for use in the synthesis of specialty chemicals and functional materials, such as ligands for catalysts or organic electronic components.

Basic Information

Product Name	5-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid
CAS No.	1352398-48-1
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	5-Fluoroimidazo[1,2-a]pyridine-2-carboxylic acid; 2-Carboxy-5-fluoroimidazo[1,2-a]pyridine; 5-Fluoro-1H-imidazo[1,2-a]pyridine-2-carboxylic acid; 1352398-48-1; 5-F-Imidazo[1,2-a]Pyridine-2-COOH; 5-Fluoroimidazopyridine-2-carboxylic acid; 5-F-Imidazopyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-Imidazo[1,2-A]Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical intermediates in development and production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.