Description

2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxylic Acid Methyl Ester is a high-purity heterocyclic building block of significant importance in modern pharmaceutical research and development. This compound serves as a critical synthetic intermediate for the construction of complex molecules targeting various therapeutic areas. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs). Its specific structure makes it a valuable scaffold for medicinal chemists.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates.
• Medicinal Chemistry Research: Used as a versatile building block for structure-activity relationship (SAR) studies and library synthesis.
• Biochemical Tool Compound: Employed in the development of probes for studying biological pathways and target validation.
• Agrochemical Research: Potential intermediate in the development of new herbicides or fungicides.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxylic Acid Methyl Ester
CAS No.	1352396-67-8
Molecular Formula	C8H6ClN3O2
Molecular Weight	211.60 g/mol
Synonyms	Methyl 2-chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate; 2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid methyl ester; 2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylic acid, methyl ester; 2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-carboxylate, methyl; 2-Chloro-7H-pyrrolo[2,3-d]pyrimidine-5-methyl carboxylate
EINECS	Contact for details

Quality Control

Our 2-Chloro-7H-Pyrrolo[2,3-D]Pyrimidine-5-Carboxylic Acid Methyl Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.