Description

6-Fluoro-4-Oxo-1,4-Dihydro-[1,5]Naphthyridine-3-Carboxylic Acid is a high-purity, fluorinated naphthyridine derivative serving as a critical advanced pharmaceutical intermediate. This compound matters for its role in constructing complex molecular scaffolds, particularly in the development of novel active pharmaceutical ingredients (APIs) with enhanced biological activity and selectivity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the synthesis of next-generation therapeutics, including kinase inhibitors and antimicrobial agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting specific enzymes and receptors.
• Kinase Inhibitor Development: Used in research and production of small molecule inhibitors for oncology and inflammatory disease applications.
• Antimicrobial Agent Synthesis: Serves as a core structure for developing new classes of antibacterial and antifungal compounds.
• Chemical Research & Development: Employed in academic and industrial R&D for exploring new chemical entities and structure-activity relationships (SAR).
• Process Chemistry: Utilized in route scouting and scale-up processes for the manufacture of complex active pharmaceutical ingredients (APIs).
• Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	6-Fluoro-4-Oxo-1,4-Dihydro-[1,5]Naphthyridine-3-Carboxylic Acid
CAS No.	1352395-75-5
Molecular Formula	C9H5FN2O3
Molecular Weight	208.15 g/mol
Synonyms	6-Fluoro-1,4-dihydro-4-oxo[1,5]naphthyridine-3-carboxylic acid; 6-Fluoro-4-oxo-1,4-dihydro[1,5]naphthyridine-3-carboxylic acid; 3-Carboxy-6-fluoro-1,4-dihydro-4-oxo-1,5-naphthyridine; 6-Fluoro-4-oxo-1H-[1,5]naphthyridine-3-carboxylic acid; 1,5-Naphthyridine-3-carboxylic acid, 1,4-dihydro-6-fluoro-4-oxo-; 1352395-75-5; 6-Fluoro-4-oxo-1,4-dihydro-[1,5]naphthyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Fluoro-4-Oxo-1,4-Dihydro-[1,5]Naphthyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the high-purity standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is light-sensitive and should be handled and stored away from strong light sources. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.