Description

1H-Pyrazolo[4,3-B]Pyridine-6-Carbonitrile is a high-value nitrogen-containing heterocyclic building block with the CAS registry number 1352395-13-1. This compound is a critical intermediate in modern pharmaceutical research and development, particularly for its role in constructing novel bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing advanced compounds with potential therapeutic or functional properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection and pest management.
• Material Science: Serves as a precursor for constructing complex organic frameworks and functional materials.
• Chemical Biology: Employed as a molecular probe or a core scaffold in medicinal chemistry and hit-to-lead optimization programs.
• Academic & Contract Research: Essential for exploratory synthetic chemistry and methodology development in university and CRO laboratories.

Basic Information

Product Name	1H-Pyrazolo[4,3-B]Pyridine-6-Carbonitrile
CAS No.	1352395-13-1
Molecular Formula	C7H4N4
Molecular Weight	144.14 g/mol
Synonyms	6-Cyano-1H-pyrazolo[4,3-b]pyridine; 1H-Pyrazolo[4,3-b]pyridine-6-carbonitrile; Pyrazolo[4,3-b]pyridine-6-carbonitrile; 6-CN-Pyrazolopyridine; 1352395-13-1 (CAS Name)
EINECS	Contact for details

Quality Control

Our 1H-Pyrazolo[4,3-B]Pyridine-6-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.