Description

Chol-6-En-24-Oic Acid, 3,7-Bis[(Trimethylsilyl)Oxy]-, Phenylmethyl Ester, (3α,5β)- is a key protected intermediate in the synthesis of complex bile acid derivatives and steroidal compounds. This high-purity chemical is critical for pharmaceutical research and development, offering a reliable building block for creating novel therapeutic agents. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for advanced synthetic applications.

Application

• Pharmaceutical Intermediate: Serves as a crucial synthetic precursor for the development of novel bile acid-based drugs and steroidal active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for exploring new synthetic pathways and studying the structure-activity relationships of steroidal compounds.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex molecules in pilot plant and manufacturing settings.
• Bioconjugate Synthesis: Acts as a starting material for creating labeled or modified steroidal probes used in biochemical and diagnostic research.
• Fine Chemical Production: Integral to the multi-step synthesis of high-value, specialized chemicals for various industrial applications.

Basic Information

Product Name	Chol-6-En-24-Oic Acid, 3,7-Bis[(Trimethylsilyl)Oxy]-, Phenylmethyl Ester, (3α,5β)-
CAS No.	1352328-65-4
Molecular Formula	C39H64O4Si2
Molecular Weight	653.1 g/mol
Synonyms	3α,7β-Bis(trimethylsilyloxy)-5β-cholan-24-oic Acid Benzyl Ester; Benzyl 3α,7β-Bis(trimethylsilyloxy)-5β-cholan-24-oate; (3α,5β)-3,7-Bis[(Trimethylsilyl)oxy]chol-6-en-24-oic Acid Phenylmethyl Ester; Protected Chenodeoxycholic Acid Benzyl Ester; TMS-protected Bile Acid Ester; Benzyl Chenodeoxycholate 3,7-bis(trimethylsilyl) Ether
EINECS	Contact for details

Quality Control

Our Chol-6-En-24-Oic Acid, 3,7-Bis[(Trimethylsilyl)Oxy]-, Phenylmethyl Ester, (3α,5β)- is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.