Description

Ethyl 3,4-Difluoro-2-Methylbenzoate is a high-purity fluorinated aromatic ester building block essential for advanced organic synthesis. This compound is valued for its role in introducing the difluoromethylbenzoate moiety, a key structural feature in the development of active pharmaceutical ingredients and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, improving their dielectric anisotropy and thermal stability.
• Polymer Modification: Employed to incorporate fluorinated aromatic units into specialty polymers, enhancing their chemical resistance, thermal properties, and surface characteristics.
• Chemical Research & Development: A versatile reagent for academic and industrial research focused on organofluorine chemistry, cross-coupling reactions, and ester transformations.

Basic Information

Product Name	Ethyl 3,4-Difluoro-2-Methylbenzoate
CAS No.	1352208-34-4
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	Ethyl 3,4-Difluoro-o-toluate; 2-Methyl-3,4-difluorobenzoic Acid Ethyl Ester; Benzoic acid, 3,4-difluoro-2-methyl-, ethyl ester; 3,4-Difluoro-2-methylbenzoic acid ethyl ester; Ethyl 3,4-difluoro-2-methylbenzoate
EINECS	Contact for details

Quality Control

Our Ethyl 3,4-Difluoro-2-Methylbenzoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.