Description

4-Methyl-n-(Piperidin-4-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is a high-value, multi-functional boronic ester derivative that serves as a critical building block in modern synthetic chemistry. This compound matters because it provides a protected boronic acid functionality, offering superior stability and handling characteristics for complex coupling reactions. Pharmaceutical R&D and agrochemical manufacturers need it as a key intermediate for constructing novel active molecules via Suzuki-Miyaura cross-coupling.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex heterocyclic architectures.
• Material Science Research: Serves as a building block for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the design and synthesis of molecular probes and labeled compounds for biological target identification and validation.
• Academic & Contract Research: Essential for methodology development and exploring new synthetic routes in academic laboratories and CROs (Contract Research Organizations).
• Custom Synthesis & Scale-Up: A starting material for custom synthesis projects, offering a path to gram-to-kilogram scale production of bespoke boronic acid derivatives.

Basic Information

Product Name	4-Methyl-n-(Piperidin-4-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine
CAS No.	1351995-08-8
Molecular Formula	C18H30BN3O2
Molecular Weight	331.27 g/mol
Synonyms	4-Methyl-N-(piperidin-4-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-amine; 2-Amino-4-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(piperidin-4-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methyl-N-(piperidin-4-yl)pyridin-2-amine; Boronic ester pyridine derivative; Pinacol boronate pyridine intermediate; CAS 1351995-08-8
EINECS	Contact for details

Quality Control

Our 4-Methyl-n-(Piperidin-4-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with full batch traceability are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.