Description

4-Methyl-2-(2-Methyl-1H-Imidazol-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-value, multi-functional heterocyclic compound that serves as a critical building block in modern synthetic chemistry. Its core value lies in the combination of a pyridine core with both an imidazole substituent and a pinacol boronate ester group, making it a versatile intermediate for cross-coupling reactions and pharmaceutical synthesis. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to develop new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Suzuki-Miyaura Cross-Coupling Reactions: The pinacol boronate ester functional group makes it an ideal partner for palladium-catalyzed coupling with aryl/heteroaryl halides to construct complex biaryl systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand Synthesis for Catalysis: The imidazole-pyridine motif can be utilized to create novel chelating ligands for transition metal catalysts.
• Material Science: Building block for organic electronic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Chemical Biology Probes: Useful for creating tagged molecules to study biological pathways and protein interactions.

Basic Information

Product Name	4-Methyl-2-(2-Methyl-1H-Imidazol-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1351995-06-6
Molecular Formula	C17H24BN3O2
Molecular Weight	313.20 g/mol
Synonyms	2-(2-Methyl-1H-imidazol-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-4-methylpyridine; 4-Methyl-2-(2-methylimidazol-1-yl)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(2-methyl-1H-imidazol-1-yl)-4-methylpyridine; Boronic acid, B-[2-(2-methyl-1H-imidazol-1-yl)-4-methyl-5-pyridinyl]-, pinacol ester; CAS 1351995-06-6; Pinacol [2-(2-methyl-1H-imidazol-1-yl)-4-methyl-5-pyridinyl]boronate
EINECS	Contact for details

Quality Control

Every batch of 4-Methyl-2-(2-Methyl-1H-Imidazol-1-Yl)-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent batch-to-batch quality suitable for demanding research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.