Description

3-Iodo-1H-Pyrazolo[4,3-C]Pyridin-4-Amine is a high-value, heterocyclic organic compound featuring a fused pyrazolopyridine core functionalized with iodine and amine groups. This specific molecular architecture makes it a critical pharmaceutical intermediate and a versatile building block for medicinal chemistry research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and biotechnology sectors for the synthesis of novel active compounds targeting various disease pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates, particularly in oncology and anti-inflammatory research.
• Medicinal Chemistry Building Block: Used for structure-activity relationship (SAR) studies and library synthesis due to its reactive iodine and amine handles for further functionalization.
• Agrochemical Research: Serves as a core structure for developing new active ingredients for crop protection products.
• Chemical Biology Probe Development: Employed in the creation of molecular probes to study biological processes and protein functions.
• Material Science Research: Potential use as a monomer or precursor for constructing specialized organic electronic materials or metal-organic frameworks (MOFs).

Basic Information

Item	Details
Product Name	3-Iodo-1H-Pyrazolo[4,3-C]Pyridin-4-Amine
CAS No.	1351479-27-0
Molecular Formula	C6H5IN4
Molecular Weight	260.03 g/mol
Synonyms	3-Iodo-1H-pyrazolo[4,3-c]pyridin-4-amine; 4-Amino-3-iodo-1H-pyrazolo[4,3-c]pyridine; 3-Iodo-4-amino-1H-pyrazolo[4,3-c]pyridine; 1H-Pyrazolo[4,3-c]pyridin-4-amine, 3-iodo-; 1351479-27-0; Pyrazolopyridine derivative; Iodopyrazolopyridine amine
EINECS	Contact for details

Quality Control

Our 3-Iodo-1H-Pyrazolo[4,3-C]Pyridin-4-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. The compound is light-sensitive and easily oxidized; allow the sealed container to reach room temperature before opening to minimize moisture ingress and degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.