Description

1H-Pyrazolo[3,4-B]Pyridine, 5-Fluoro-3-Iodo- is a high-value, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique halogenated pyrazolopyridine core serves as a critical scaffold for constructing complex molecules with tailored biological and electronic properties. Pharmaceutical and agrochemical researchers need it for developing new active ingredients, while material scientists utilize it in the creation of specialty polymers and organic electronic components.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated heterocyclic structure for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, light-emitting diodes (OLEDs), and other functional materials due to its electron-deficient aromatic system.
• Chemical Biology: Employed as a molecular probe or tag in bioconjugation and labeling strategies to study biological processes.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create diverse compound libraries.
• Academic & Contract Research: Essential for synthetic methodology development and discovery chemistry within research institutions and CROs.

Basic Information

Product Name	1H-Pyrazolo[3,4-B]Pyridine, 5-Fluoro-3-Iodo-
CAS No.	1350653-23-4
Molecular Formula	C6H3FIN3
Molecular Weight	262.99 g/mol
Synonyms	5-Fluoro-3-iodo-1H-pyrazolo[3,4-b]pyridine; 3-Iodo-5-fluoropyrazolo[3,4-b]pyridine; 5-Fluoro-3-iodopyrazolo[3,4-b]pyridine; 1H-Pyrazolo[3,4-b]pyridine, 5-fluoro-3-iodo-; 1350653-23-4; 5-Fluoro-3-iodo-1H-pyrazolo[3,4-b]pyridine; 3-Iodo-5-fluoro-1H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrazolo[3,4-B]Pyridine, 5-Fluoro-3-Iodo- is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as purity, identity, and impurity profiles to support your R&D and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.