Description

16-Oxo Ethynyl Estradiol is a high-purity synthetic steroid derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in enabling the synthesis of novel therapeutic agents, particularly in the fields of endocrinology and oncology. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology industries who are developing next-generation hormone therapies and targeted treatments.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Hormone Research: Used in biochemical studies to investigate estrogen receptor interactions and metabolic pathways.
• Drug Discovery: Serves as a precursor in medicinal chemistry for creating new chemical entities with potential therapeutic applications.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Tool Compound: Utilized in vitro and in vivo studies to modulate specific biological targets related to hormonal function.

Basic Information

Product Name	16-Oxo Ethynyl Estradiol
CAS No.	1350468-76-6
Molecular Formula	C20H24O3
Molecular Weight	312.41 g/mol
Synonyms	16-Oxoethynylestradiol; 17α-Ethynyl-16-oxoestra-1,3,5(10)-triene-3,17β-diol; 17α-Ethynyl-16-oxoestradiol; 16-Oxo-17α-ethynylestradiol; 16-Keto Ethynyl Estradiol; 16-Oxo EE2; 16-Oxo-EE2; 16-Oxo-17α-ethynyl-1,3,5(10)-estratriene-3,17β-diol
EINECS	Contact for details

Quality Control

Our 16-Oxo Ethynyl Estradiol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.