Description

(6α,17β)-Estratriol 3,17-Dipentanoate is a high-purity, synthetic steroid derivative, specifically a dipentanoate ester of estriol. This compound is of significant value in pharmaceutical research and development, serving as a key intermediate or reference standard for the synthesis of novel steroidal drugs and hormone analogs. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and academic institutions focused on endocrinology, oncology, and metabolic disease research.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced steroidal active pharmaceutical ingredients (APIs) and prodrugs.
• Reference Standard: Used for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in studies investigating estrogen receptor (ER) binding affinity, metabolism, and hormonal signaling pathways.
• Prodrug Development: The esterified form can be utilized to enhance the lipophilicity and bioavailability of parent hormone molecules in drug design.
• Academic & Contract Research: Serves as a reagent for fundamental research in steroid chemistry and pharmacology at universities and CROs.

Basic Information

Product Name	(6α,17β)-Estratriol 3,17-Dipentanoate
CAS No.	1350468-75-5
Molecular Formula	C28H42O5
Molecular Weight	458.64 g/mol
Synonyms	Estriol 3,17-Dipentanoate; 3,17-Bis(pentanoyloxy)-estra-1,3,5(10)-triene-6,16,17-triol; Estratriol Dipentanoate; 6α,17β-Estriol 3,17-dipentanoate; 16,17-Dihydroxy-3-(pentanoyloxy)-estra-1,3,5(10)-trien-17-yl pentanoate
EINECS	Contact for details

Quality Control

Our (6α,17β)-Estratriol 3,17-Dipentanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.