Description

5-Nitro-2-(Oxetan-3-yloxy)pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique oxetane-pyridine hybrid structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its specific molecular framework into new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its versatile reactive sites.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides and pesticides with enhanced efficacy.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing for specialized chemical products.
• Academic Research: Utilized in university and institutional labs for exploring new organic reactions and heterocyclic chemistry.
• Chemical Library Development: A valuable scaffold for creating diverse compound libraries for high-throughput screening.

Basic Information

Product Name	5-Nitro-2-(Oxetan-3-yloxy)pyridine
CAS No.	1349719-05-6
Molecular Formula	C8H8N2O4
Molecular Weight	196.16 g/mol
Synonyms	2-(Oxetan-3-yloxy)-5-nitropyridine; 5-Nitro-2-(3-oxetanyloxy)pyridine; Pyridine, 5-nitro-2-(3-oxetanyloxy)-; 1349719-05-6; 3-((5-Nitropyridin-2-yl)oxy)oxetane; Oxetan-3-yl 5-nitropyridin-2-yl ether
EINECS	Contact for details

Quality Control

Our 5-Nitro-2-(Oxetan-3-yloxy)pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.