Description

1-Cyclobutyl-1H-Pyrazole-4-Carboxylic Acid is a high-value heterocyclic building block essential for modern pharmaceutical and agrochemical research and development. Its core value lies in its versatile pyrazole-carboxylic acid scaffold, which serves as a critical intermediate for constructing complex molecules with targeted biological activity. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel active pharmaceutical ingredients (APIs) and by researchers in agrochemical discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study enzyme function and biological mechanisms.
• Material Science Research: Potential intermediate for the development of specialty polymers or organic electronic materials due to its aromatic and carboxylic acid functionality.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploratory synthesis of new chemical entities.

Basic Information

Product Name	1-Cyclobutyl-1H-Pyrazole-4-Carboxylic Acid
CAS No.	1349718-35-9
Molecular Formula	C8H10N2O2
Molecular Weight	166.18 g/mol
Synonyms	1-Cyclobutyl-1H-pyrazole-4-carboxylic acid; 1-Cyclobutyl-4-pyrazolecarboxylic Acid; 4-Pyrazolecarboxylic acid, 1-cyclobutyl-; 1-Cyclobutylpyrazole-4-carboxylic Acid; Cyclobutyl-pyrazole-carboxylic acid; 1H-Pyrazole-4-carboxylic acid, 1-cyclobutyl-; 1349718-35-9 (CAS); CBZ-4-COOH (abbreviation)
EINECS	Contact for details

Quality Control

Our 1-Cyclobutyl-1H-Pyrazole-4-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades and analytical packages are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.