Description

4-(Hydrazinomethyl)Pyridine Trihydrochloride is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the reactive hydrazine moiety, which enables the formation of hydrazones and other nitrogen-containing heterocycles with precision. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its ability to form stable heterocyclic scaffolds.
• Ligand and Chelating Agent Precursor: Serves as a starting material for creating specialized ligands used in catalysis and metal complexation studies.
• Bioconjugation and Linker Chemistry: The hydrazine group is utilized for bioconjugation strategies, attaching payloads to antibodies or other biomolecules in ADC (Antibody-Drug Conjugate) development.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic frameworks for electronic or sensory applications.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study enzyme activity and biological pathways.

Basic Information

Product Name	4-(Hydrazinomethyl)Pyridine Trihydrochloride
CAS No.	1349717-75-4
Molecular Formula	C6H9N3 • 3HCl
Molecular Weight	239.53 g/mol
Synonyms	4-(Hydrazinylmethyl)pyridine trihydrochloride; 4-Pyridinemethanamine, N-amino-, trihydrochloride; 4-(Aminomethyl)pyridine hydrazone trihydrochloride; (Pyridin-4-yl)methanamine hydrazone trihydrochloride; 4-Hydrazinomethylpyridine trihydrochloride; 4-Picolylhydrazine trihydrochloride; γ-Picolylhydrazine trihydrochloride; 4-(Hydrazonomethyl)pyridine hydrochloride (salt)
EINECS	Contact for details

Quality Control

Our 4-(Hydrazinomethyl)Pyridine Trihydrochloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay (Titration)	97.0% - 103.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.