Description

(R)-1-(Pentan-3-Yl)Pyrrolidin-3-Amine Dihydrochloride is a high-purity chiral amine salt, a critical building block in advanced pharmaceutical synthesis. This compound matters as a key intermediate for developing novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and receptor-targeted therapies. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the development of enantiomerically pure drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially for neurological and psychiatric applications.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in catalytic asymmetric reactions to induce stereoselectivity.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for transition metal catalysis or organocatalysts.
• Reference Standard: Used as an analytical standard for method development and quality control in pharmaceutical manufacturing.
• Preclinical Development: Supplied in development quantities for formulation studies, pharmacokinetic, and toxicological evaluations.

Basic Information

Product Name	(R)-1-(Pentan-3-Yl)Pyrrolidin-3-Amine Dihydrochloride
CAS No.	1349702-28-8
Molecular Formula	C9H20N2·2HCl
Molecular Weight	225.19 g/mol
Synonyms	(3R)-1-(Pentan-3-yl)pyrrolidin-3-amine dihydrochloride; (R)-1-(Pentan-3-yl)pyrrolidin-3-amine hydrochloride (1:2); (R)-3-Amino-1-(pentan-3-yl)pyrrolidine dihydrochloride; (R)-1-(1-Ethylpropyl)-3-aminopyrrolidine dihydrochloride; (R)-1-(3-Pentyl)pyrrolidin-3-amine dihydrochloride; (R)-Pentan-3-yl-pyrrolidin-3-yl-amine dihydrochloride; (R)-1-(1-Ethylpropyl)-3-pyrrolidinamine dihydrochloride
EINECS	Contact for details

Quality Control

Our (R)-1-(Pentan-3-Yl)Pyrrolidin-3-Amine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.