Description

Methyl 1-Boc-3-Allylpiperidine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold protected by a tert-butoxycarbonyl (Boc) group. This compound is of significant value for medicinal chemistry research and process development, serving as a versatile building block for the synthesis of complex bioactive molecules. It is primarily utilized by R&D chemists and process scientists in the pharmaceutical and biotechnology industries for creating novel drug candidates, particularly in central nervous system (CNS) and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR).
• Process Chemistry & Scale-Up: Serves in route scouting and development for the commercial manufacturing of complex molecules.
• Protease Inhibitor Synthesis: A potential precursor in the development of protease inhibitors due to its functionalized piperidine core.
• Alkaloid & Natural Product Analog Synthesis: Employed in the construction of piperidine-containing alkaloid analogs and natural product derivatives.
• Chemical Biology & Probe Development: Useful for creating chemical probes to study biological pathways and protein function.

Basic Information

Product Name	Methyl 1-Boc-3-Allylpiperidine-3-Carboxylate
CAS No.	1349644-17-2
Molecular Formula	C15H25NO4
Molecular Weight	283.36 g/mol
Synonyms	1-Boc-3-Allyl-3-piperidinecarboxylic Acid Methyl Ester; Methyl 3-Allyl-1-[(2-methylpropan-2-yl)oxycarbonyl]piperidine-3-carboxylate; 3-Allyl-1-Boc-piperidine-3-carboxylic Acid Methyl Ester; 1-(tert-Butoxycarbonyl)-3-allylpiperidine-3-carboxylic Acid Methyl Ester; tert-Butyl 3-Allyl-3-(methoxycarbonyl)piperidine-1-carboxylate; 1-N-Boc-3-Allylpiperidine-3-Carboxylic Acid Methyl Ester; 3-Allyl-1-N-Boc-piperidine-3-carboxylic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Methyl 1-Boc-3-Allylpiperidine-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring the material is suitable for advanced research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.