Description

2-Amino-5-Iodonicotinonitrile is a high-value, halogenated pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both an amino and a cyano group adjacent to an iodine atom, makes it an exceptionally versatile intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Ligand Synthesis: Serves as a starting material for creating specialized ligands used in catalysis and material science.
• Functional Material Development: Employed in the research of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological processes and enzyme functions.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form more complex biaryl structures.

Basic Information

Product Name	2-Amino-5-Iodonicotinonitrile
CAS No.	1347815-41-1
Molecular Formula	C6H4IN3
Molecular Weight	245.02 g/mol
Synonyms	5-Iodo-2-aminonicotinonitrile; 2-Amino-5-iodo-3-cyanopyridine; 3-Cyano-5-iodopyridin-2-amine; 5-Iodo-2-aminopyridine-3-carbonitrile; 2-Amino-5-iodopyridine-3-carbonitrile; 1347815-41-1; 5-Iodo-2-amino-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Iodonicotinonitrile is produced and tested under strict quality management protocols to ensure consistency and purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity (typically ≥95% by HPLC), identity confirmation, and impurity profiles. Our quality system is designed to meet the stringent requirements of pharmaceutical and advanced material research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified for optimal long-term stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.