Description

2-Chloro-6-(2,2,2-Trifluoroethoxy)Pyridin-4-Amine is a high-value, functionalized pyridine derivative serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both chloro and trifluoroethoxy substituents, makes it an essential intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoroethoxy group can enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold or labeling reagent in the design of molecular probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Chloro-6-(2,2,2-Trifluoroethoxy)Pyridin-4-Amine
CAS No.	1346809-43-5
Molecular Formula	C7H6ClF3N2O
Molecular Weight	226.58 g/mol
Synonyms	4-Amino-2-chloro-6-(2,2,2-trifluoroethoxy)pyridine; 2-Chloro-6-(2,2,2-trifluoroethoxy)-4-pyridinamine; 2-Chloro-6-(2,2,2-trifluoroethoxy)pyridin-4-ylamine; 4-Pyridinamine, 2-chloro-6-(2,2,2-trifluoroethoxy)-; 2-Chloro-6-(trifluoroethoxy)pyridin-4-amine
EINECS	Contact for details

Quality Control

Every batch of 2-Chloro-6-(2,2,2-Trifluoroethoxy)Pyridin-4-Amine is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.