Description

4-Chloro-2-(2,2,2-trifluoroethoxy)pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a halogenated pyridine core with a trifluoroethoxy side chain, makes it indispensable for introducing specific physicochemical properties into target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules requiring fluorinated motifs to enhance metabolic stability, bioavailability, or binding affinity.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms can improve lipophilicity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers or organic electronic materials that benefit from fluorine incorporation.
• Chemical Biology Probes: Useful for synthesizing tagged molecules or probes for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	4-Chloro-2-(2,2,2-trifluoroethoxy)pyridine
CAS No.	1346809-11-7
Molecular Formula	C7H5ClF3NO
Molecular Weight	211.57 g/mol
Synonyms	4-Chloro-2-(2,2,2-trifluoroethoxy)pyridine; 2-(2,2,2-Trifluoroethoxy)-4-chloropyridine; 4-Chloro-2-(trifluoroethoxy)pyridine; Pyridine, 4-chloro-2-(2,2,2-trifluoroethoxy)-; 1346809-11-7
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(2,2,2-trifluoroethoxy)pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.