Description

tert-Butyl 3-(3-Amino-1H-Pyrazol-5-Yl)Azetidine-1-Carboxylate is a high-purity, protected heterocyclic building block of significant interest in advanced organic synthesis. This compound is valued for its bifunctional azetidine and aminopyrazole moieties, which serve as key scaffolds for constructing complex molecular architectures. It is primarily utilized by pharmaceutical and agrochemical R&D organizations for the development of novel active ingredients, including kinase inhibitors and other biologically relevant small molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, particularly in oncology and anti-inflammatory research.
• Kinase Inhibitor Scaffold: Serves as a core structural element for designing and optimizing potent and selective kinase inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probe Synthesis: Employed to create tool compounds for studying biological pathways and target validation.
• Peptidomimetic Chemistry: The azetidine ring acts as a constrained surrogate for amino acids in peptide-based drug design.
• Library Synthesis for HTS: A valuable building block for generating diverse compound libraries for high-throughput screening campaigns.

Basic Information

Product Name	tert-Butyl 3-(3-Amino-1H-Pyrazol-5-Yl)Azetidine-1-Carboxylate
CAS No.	1346674-11-0
Molecular Formula	C11H18N4O2
Molecular Weight	238.29 g/mol
Synonyms	1-Boc-3-(3-amino-1H-pyrazol-5-yl)azetidine; 3-(3-Amino-1H-pyrazol-5-yl)azetidine-1-carboxylic acid tert-butyl ester; tert-Butyl 3-(3-amino-1H-pyrazol-5-yl)azetidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-(3-amino-1H-pyrazol-5-yl)azetidine; Azetidine-1-carboxylic acid, 3-(3-amino-1H-pyrazol-5-yl)-, 1,1-dimethylethyl ester; 1346674-11-0; Boc-3-(3-Amino-1H-pyrazol-5-yl)azetidine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-(3-Amino-1H-Pyrazol-5-Yl)Azetidine-1-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable, and specifications can be aligned with client requirements for advanced pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.