Description

2-(Acetylamino)-2-[2-(4-Bromo-2-Chlorophenyl)Ethyl]Propanedioic Acid 1,3-Diethyl Ester is a high-value, multi-functional chemical intermediate characterized by its complex molecular architecture incorporating bromo, chloro, and acetylamino substituents. This compound matters for its role as a critical building block in the synthesis of advanced pharmaceutical compounds and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where the halogenated phenyl group contributes to biological activity and environmental stability.
• Chemical Research & Development: Acts as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the creation of compound libraries for high-throughput screening.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale production of complex organic molecules.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring this specific molecular framework.

Basic Information

Product Name	2-(Acetylamino)-2-[2-(4-Bromo-2-Chlorophenyl)Ethyl]Propanedioic Acid 1,3-Diethyl Ester
CAS No.	1346604-54-3
Molecular Formula	C17H21BrClNO5
Molecular Weight	434.71 g/mol
Synonyms	Diethyl 2-acetamido-2-[2-(4-bromo-2-chlorophenyl)ethyl]propanedioate; 2-Acetamido-2-[2-(4-bromo-2-chlorophenyl)ethyl]malonic Acid Diethyl Ester; Propanedioic acid, 2-(acetylamino)-2-[2-(4-bromo-2-chlorophenyl)ethyl]-, 1,3-diethyl ester; 1346604-54-3; CAS 1346604-54-3; 2-(Acetylamino)-2-[2-(4-bromo-2-chlorophenyl)ethyl]malonic Acid Diethyl Ester
EINECS	Contact for details

Quality Control

Our 2-(Acetylamino)-2-[2-(4-Bromo-2-Chlorophenyl)Ethyl]Propanedioic Acid 1,3-Diethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed when not in use to prevent moisture absorption. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.