Description

2,6-Difluorobenzyl Azide-D2 is a deuterated organic azide compound, specifically designed for advanced research and development applications. This isotopically labeled reagent is critical for mechanistic studies, metabolic pathway tracing, and the synthesis of deuterated active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D teams, agrochemical scientists, and academic researchers working in medicinal chemistry and isotope labeling.

Application

• Click Chemistry Reagent: Acts as a key building block in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions for synthesizing deuterated triazole derivatives.
• Isotope Labeling in Medicinal Chemistry: Used for the preparation of deuterium-labeled drug candidates to study pharmacokinetics, metabolic stability, and bioavailability.
• Pharmaceutical Intermediate: Serves as a versatile synthon in the multi-step synthesis of complex, fluorinated, and deuterated bioactive molecules.
• Agrochemical Research: Employed in the development of novel, isotopically labeled pesticides and herbicides for environmental fate and metabolism studies.
• Proteomics & Bioconjugation: Facilitates the site-specific labeling of proteins and biomolecules for mass spectrometry-based analysis and imaging.
• Material Science: Used in the synthesis of specialized polymers and advanced materials where deuterium incorporation modifies physical properties.

Basic Information

Product Name	2,6-Difluorobenzyl Azide-D2
CAS No.	1346600-83-6
Molecular Formula	C7H3D2F2N3
Molecular Weight	171.13 g/mol
Synonyms	2,6-Difluoro-α-azidotoluene-D2; (Azidomethyl)-2,6-difluorobenzene-D2; 1-(Azidomethyl)-2,6-difluorobenzene-D2; 2,6-Difluorobenzyl-d2 Azide; Deutero 2,6-Difluorobenzyl Azide; 2,6-Difluorobenzyl Azide (benzyl-d2); α-Azido-2,6-difluorotoluene-D2
EINECS	Contact for details

Quality Control

Every batch of 2,6-Difluorobenzyl Azide-D2 is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure product identity, purity, and isotopic enrichment meet the stringent requirements of research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting results from NMR, HPLC, and MS analysis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, heat, and sources of ignition. Due to the azide functional group, handle and store with appropriate precautions.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Deuterium Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.