Description

Ethyl n-Boc-2-thiomorpholinecarboxylate is a high-purity, protected thiomorpholine derivative used as a critical building block in advanced organic synthesis. This compound is essential for medicinal chemistry research and development, enabling the efficient construction of complex molecules with potential therapeutic activity. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers involved in the synthesis of novel drug candidates, particularly those targeting the central nervous system.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of active pharmaceutical ingredients (APIs) containing the thiomorpholine scaffold.
• Medicinal Chemistry Research: Used in the design and synthesis of compound libraries for high-throughput screening and structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: Serves as a constrained amino acid analog for creating novel peptide-like molecules with enhanced metabolic stability.
• Ligand Development: Employed in the synthesis of specialized ligands for catalysis or receptor binding studies.
• Custom Synthesis Projects: A versatile starting material for contract research organizations (CROs) and CDMOs working on client-specific molecules.

Basic Information

Product Name	Ethyl n-Boc-2-thiomorpholinecarboxylate
CAS No.	1346597-50-9
Molecular Formula	C12H21NO4S
Molecular Weight	275.36 g/mol
Synonyms	Ethyl 1-Boc-2-thiomorpholinecarboxylate; Ethyl 1-(tert-Butoxycarbonyl)-2-thiomorpholinecarboxylate; 2-Thiomorpholinecarboxylic acid, 1-(1,1-dimethylethyl) ester, ethyl ester; 1-Boc-2-thiomorpholinecarboxylic acid ethyl ester; tert-Butyl 2-(ethoxycarbonyl)thiomorpholine-1-carboxylate; Ethyl 1-N-Boc-2-thiomorpholinecarboxylate; N-Boc-2-thiomorpholinecarboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl n-Boc-2-thiomorpholinecarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.