Description

5-(Bromomethyl)-5-Methyl-1,3-Dioxan-2-One is a specialized brominated cyclic carbonate ester, a high-value building block in advanced organic synthesis. This compound matters for its unique bifunctional reactivity, offering both a bromomethyl handle for nucleophilic substitution and a cyclic carbonate moiety that can undergo ring-opening reactions. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the introduction of functionalized side chains in drug discovery programs, particularly for anticancer and antiviral agents.
• Polymer Chemistry: Serves as a monomer or co-monomer for synthesizing functional polycarbonates and polyurethanes with pendant reactive groups for further modification.
• Linker in Bioconjugation: Used to create cleavable or stable linkages between drug molecules and targeting ligands, such as antibodies, in antibody-drug conjugate (ADC) development.
• Agrochemical Synthesis: Employed in the synthesis of novel herbicides and fungicides where the cyclic carbonate structure can enhance bioavailability or environmental profile.
• Material Science: A precursor for surface-modifying agents and cross-linkers that impart specific chemical functionalities to polymers and coatings.
• Organic Synthesis Reagent: Utilized in academic and industrial R&D for constructing heterocycles and complex ethers via its versatile reactive sites.

Basic Information

Item	Detail
Product Name	5-(Bromomethyl)-5-Methyl-1,3-Dioxan-2-One
CAS No.	1346562-84-2
Molecular Formula	C7H9BrO4
Molecular Weight	237.05 g/mol
Synonyms	5-(Bromomethyl)-5-methyl-1,3-dioxan-2-one; 5-Methyl-5-(bromomethyl)-1,3-dioxan-2-one; 2-Oxo-5-methyl-5-(bromomethyl)-1,3-dioxane; 5-(Bromomethyl)-5-methyl-2-oxo-1,3-dioxane; Bromomethyl methyl dioxanone; Cyclic carbonate bromomethyl derivative
EINECS	Contact for details

Quality Control

Our 5-(Bromomethyl)-5-Methyl-1,3-Dioxan-2-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.