Description

4-Chloro-3-Cyclopropylpyridine is a high-purity, versatile heterocyclic building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a chloropyridine moiety and a cyclopropyl group, makes it a critical intermediate for constructing complex molecules with tailored biological and physical properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-infective therapies.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the cyclopropyl group can enhance metabolic stability and activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of organic electronic materials and functionalized polymers.
• Chemical Biology Probes: Utilized to develop molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	4-Chloro-3-Cyclopropylpyridine
CAS No.	1346544-23-7
Molecular Formula	C8H8ClN
Molecular Weight	153.61 g/mol
Synonyms	3-Cyclopropyl-4-chloropyridine; 4-Chloro-3-cyclopropyl-pyridine; Pyridine, 4-chloro-3-cyclopropyl-; 3-Cyclopropyl-4-chloro-pyridine
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Cyclopropylpyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC/GC-MS)	Conforms
Assay (HPLC)	≥97.0% (Typical 98.0-99.5%)
Related Substances (HPLC)	Total impurities ≤3.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.