Description

2-(2H-Benzo[B][1,4]Oxazin-4(3H)-Yl)-n-Benzyl-5,6,7,8-Tetrahydroquinazolin-4-Amine is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily targeted at research institutions and pharmaceutical companies engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Chemical Biology: Employed in the development of chemical probes to study biological pathways and protein functions.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and scale-up projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for synthetic methodology development and bioorganic chemistry studies.

Basic Information

Product Name	2-(2H-Benzo[B][1,4]Oxazin-4(3H)-Yl)-n-Benzyl-5,6,7,8-Tetrahydroquinazolin-4-Amine
CAS No.	1346528-06-0
Molecular Formula	C24H24N4O
Molecular Weight	384.48 g/mol
Synonyms	2-(2H-1,4-Benzoxazin-4(3H)-yl)-N-benzyl-5,6,7,8-tetrahydroquinazolin-4-amine; 2-(3,4-Dihydro-2H-1,4-benzoxazin-4-yl)-N-(phenylmethyl)-5,6,7,8-tetrahydro-4-quinazolinamine; 2-(2H-1,4-Benzoxazin-4-yl)-N-benzyl-4-amino-5,6,7,8-tetrahydroquinazoline; 1346528-06-0; N-Benzyl-2-(3,4-dihydro-2H-benzo[b][1,4]oxazin-4-yl)-5,6,7,8-tetrahydroquinazolin-4-amine
EINECS	Contact for details

Quality Control

Our 2-(2H-Benzo[B][1,4]Oxazin-4(3H)-Yl)-n-Benzyl-5,6,7,8-Tetrahydroquinazolin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.