Description

6-Iodo-3,4-Dihydro-2H-Pyrano-[3,2-B]Pyridine-8-Carboxylic Acid is a high-purity, heterocyclic carboxylic acid derivative featuring a fused pyranopyridine core structure. This compound is a critical pharmaceutical intermediate and research chemical valued for its unique halogenated scaffold, which enables the synthesis of complex bioactive molecules. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for lead optimization and novel compound library generation.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) therapeutic research.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products, leveraging its halogenated heterocyclic structure.
• Chemical Biology Probe: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential monomer or precursor for advanced organic electronic materials and metal-organic frameworks (MOFs).
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new chemical spaces.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	6-Iodo-3,4-Dihydro-2H-Pyrano-[3,2-B]Pyridine-8-Carboxylic Acid
CAS No.	1346447-29-7
Molecular Formula	C9H8INO3
Molecular Weight	305.07 g/mol
Synonyms	6-Iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridine-8-carboxylic acid; 8-Carboxy-6-iodo-3,4-dihydro-2H-pyrano[3,2-b]pyridine; 6-Iodopyranopyridine-8-carboxylic acid; 1346447-29-7; AI3-71031; ZINC000103240757; AKOS040757395; 6-iodanyl-3,4-dihydro-2H-pyrano[3,2-b]pyridine-8-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Iodo-3,4-Dihydro-2H-Pyrano-[3,2-B]Pyridine-8-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with client specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.