Description

7-Chloro-6-Iodo-2,3-Dihydro-[1,4]Dioxino[2,3-B]Pyridine is a high-value, halogenated heterocyclic building block of significant interest in advanced organic synthesis. Its core structure, featuring a fused dioxinopyridine ring system with chlorine and iodine substituents, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and anti-infective targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic scaffold.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs or charge-transport molecules.
• Chemical Biology: Employed as a probe or tag in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis: A critical starting material for contract research organizations (CROs) and CDMOs engaged in bespoke chemical synthesis projects.
• Academic Research: Utilized in universities and research institutes for methodological development in cross-coupling and heterocyclic chemistry.

Basic Information

Product Name	7-Chloro-6-Iodo-2,3-Dihydro-[1,4]Dioxino[2,3-B]Pyridine
CAS No.	1346447-23-1
Molecular Formula	C7H5ClINO2
Molecular Weight	297.48 g/mol
Synonyms	7-Chloro-6-iodo-2,3-dihydro-1,4-dioxino[2,3-b]pyridine; 2,3-Dihydro-7-chloro-6-iodo-1,4-dioxino[2,3-b]pyridine; 1,4-Dioxino[2,3-b]pyridine, 7-chloro-6-iodo-2,3-dihydro-; 7-Chloro-6-iodo-2,3-dihydro[1,4]dioxino[2,3-b]pyridine; 1346447-23-1; 7-Chloro-6-iodo-dioxinopyridine
EINECS	Contact for details

Quality Control

Our 7-Chloro-6-Iodo-2,3-Dihydro-[1,4]Dioxino[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and cGMP-intermediate synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat and incompatible materials. The container should be kept tightly sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.