Description

6-(Dimethoxymethyl)-3,4-Dihydro-2H-Pyrano[2,3-B]Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused pyranopyridine scaffold. This compound matters for its critical role as a versatile building block in the synthesis of complex, biologically active molecules, enabling the development of new therapeutic agents. It is primarily needed by research institutions and pharmaceutical companies engaged in medicinal chemistry, particularly for projects targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• CNS Drug Development: Employed in the research and synthesis of compounds targeting neurological and psychiatric conditions.
• Oncological Research: Serves as a building block for potential kinase inhibitors and other anti-cancer agents.
• Chemical Biology Probes: Utilized to create tool compounds for studying specific biological pathways and target validation.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale production under cGMP conditions for clinical trial material.

Basic Information

Product Name	6-(Dimethoxymethyl)-3,4-Dihydro-2H-Pyrano[2,3-B]Pyridine
CAS No.	1346447-17-3
Molecular Formula	C12H17NO3
Molecular Weight	223.27 g/mol
Synonyms	6-(Dimethoxymethyl)-3,4-dihydro-2H-pyrano[2,3-b]pyridine; 2H-Pyrano[2,3-b]pyridine, 6-(dimethoxymethyl)-3,4-dihydro-; 1346447-17-3; 6-(Dimethoxymethyl)dihydropyranopyridine; Dihydro-6-(dimethoxymethyl)pyrano[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-(Dimethoxymethyl)-3,4-Dihydro-2H-Pyrano[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full traceability are provided for every shipment. We support development and commercial projects with material suitable for research use and can supply grades aligned with cGMP standards for advanced pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.