Description

Methyl 7-Chloro-2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridine-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its fused dioxino-pyridine heterocyclic structure. This compound is of significant commercial value for its role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug molecules, particularly those targeting central nervous system (CNS) disorders and infectious diseases.
• Agrochemical Research: Serves as a core scaffold for developing new herbicides and fungicides with novel modes of action.
• Organic Synthesis Building Block: Used in academic and industrial R&D for constructing complex heterocyclic libraries for high-throughput screening.
• Chemical Reference Standard: Employed as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Material Science Research: Investigated as a potential monomer or precursor for specialty polymers and functional materials.

Basic Information

Product Name	Methyl 7-Chloro-2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridine-8-Carboxylate
CAS No.	1346447-13-9
Molecular Formula	C10H8ClNO4
Molecular Weight	241.63 g/mol
Synonyms	Methyl 7-chloro-2,3-dihydro-1,4-dioxino[2,3-b]pyridine-8-carboxylate; 7-Chloro-2,3-dihydro-1,4-dioxino[2,3-b]pyridine-8-carboxylic acid methyl ester; 1346447-13-9; Methyl 7-chloro-2,3-dihydro[1,4]dioxino[2,3-b]pyridine-8-carboxylate; 8-Carbomethoxy-7-chloro-2,3-dihydro-1,4-dioxino[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our production of Methyl 7-Chloro-2,3-Dihydro-[1,4]Dioxino-[2,3-B]Pyridine-8-Carboxylate adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and relevant industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.