Description

1-(5-Bromo-6-(Trifluoromethyl)Pyridin-3-Yl)Ethanone (Wxfc0699) is a high-purity, multi-functional pyridine derivative building block essential for advanced organic synthesis. Its core value lies in its unique trifluoromethyl and bromo substituents, which enable precise molecular modifications to enhance the potency and metabolic stability of target compounds. This intermediate is critically needed by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

This versatile chemical intermediate serves as a key precursor in several high-value synthetic pathways. Its primary applications include:

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting CNS disorders, oncology, and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group improves biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a molecular probe or linker in the design of activity-based probes for studying enzyme function and protein interactions.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	1-(5-Bromo-6-(Trifluoromethyl)Pyridin-3-Yl)Ethanone (Wxfc0699)
CAS No.	1346252-30-9
Molecular Formula	C8H5BrF3NO
Molecular Weight	268.03 g/mol
Synonyms	5'-Bromo-6'-(trifluoromethyl)-3-acetylpyridine; 3-Acetyl-5-bromo-6-(trifluoromethyl)pyridine; Ethanone, 1-[5-bromo-6-(trifluoromethyl)-3-pyridinyl]-; WX-FC0699; 1-(5-Bromo-6-(trifluoromethyl)pyridin-3-yl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-6-(Trifluoromethyl)Pyridin-3-Yl)Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.