Description

Isopropyl 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methylthiazole-5-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound is valued for its role as a key synthetic building block in the development of novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract development and manufacturing organizations (CDMOs) engaged in the synthesis of complex heterocyclic molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, particularly those targeting metabolic and inflammatory pathways.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the discovery of new chemical entities with thiazole core structures.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex organic molecules in custom synthesis and process development.
• API Manufacturing: Employed in the pilot-scale and commercial-scale production of active pharmaceutical ingredients requiring this specific molecular scaffold.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development, validation, and quality control in pharmaceutical analysis.

Basic Information

Product Name	Isopropyl 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methylthiazole-5-Carboxylate
CAS No.	1346238-10-5
Molecular Formula	C19H22N2O3S
Molecular Weight	358.46 g/mol
Synonyms	Isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methyl-1,3-thiazole-5-carboxylate; 5-Thiazolecarboxylic acid, 2-[3-cyano-4-(2-methylpropoxy)phenyl]-4-methyl-, 1-methylethyl ester; 1346238-10-5; 2-(3-Cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid isopropyl ester
EINECS	Contact for details

Quality Control

Our Isopropyl 2-(3-Cyano-4-Isobutoxyphenyl)-4-Methylthiazole-5-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with customer specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.