Description

2-Aza-Spiro[4.4]Nonane-4-Carboxylic Acid is a high-value, spirocyclic organic compound featuring a carboxylic acid functional group integrated into a constrained bicyclic framework. This unique structure makes it a critical advanced pharmaceutical intermediate and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and metabolic disorder targets.
• Medicinal Chemistry Building Block: Used to construct complex, three-dimensional molecular scaffolds for drug discovery libraries and structure-activity relationship (SAR) studies.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Employed in the development of molecular probes to study enzyme function and biological pathways.
• Academic and Industrial R&D: Essential for fundamental organic synthesis research and process chemistry in both university and corporate laboratory settings.

Basic Information

Product Name	2-Aza-Spiro[4.4]Nonane-4-Carboxylic Acid
CAS No.	1343864-38-9
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	4-Carboxy-2-aza-spiro[4.4]nonane; 2-Azaspiro[4.4]nonane-4-carboxylic acid; 4-Carboxy-2-azaspiro[4.4]nonane; 2-Aza-spiro[4.4]nonane-4-carboxylic acid; 2-Azaspirobicyclo[4.4]nonane-4-carboxylic acid; 4-Carboxy-2-azaspirobicyclo[4.4]nonane; 1343864-38-9
EINECS	Contact for details

Quality Control

Our 2-Aza-Spiro[4.4]Nonane-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.