Description

Ethyl 5-Cyclohexyl-1,2,4-Oxadiazole-3-Carboxylate is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique oxadiazole core imparts valuable biological and physicochemical properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to innovate new molecular entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and antimicrobials.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science: Used in the research and development of advanced polymers and liquid crystals, leveraging the stability and electronic properties of the oxadiazole ring.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	Ethyl 5-Cyclohexyl-1,2,4-Oxadiazole-3-Carboxylate
CAS No.	1343186-43-5
Molecular Formula	C11H16N2O3
Molecular Weight	224.26 g/mol
Synonyms	5-Cyclohexyl-1,2,4-oxadiazole-3-carboxylic acid ethyl ester; Ethyl 5-cyclohexyl-[1,2,4]oxadiazole-3-carboxylate; 3-Ethoxycarbonyl-5-cyclohexyl-1,2,4-oxadiazole; 1,2,4-Oxadiazole-3-carboxylic acid, 5-cyclohexyl-, ethyl ester; ECCO; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our Ethyl 5-Cyclohexyl-1,2,4-Oxadiazole-3-Carboxylate is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.