Description

4-(Tetrahydro-Furan-3-Yloxy)-Pyridin-3-Ylamine is a high-purity, advanced pharmaceutical intermediate with the CAS number 1342838-73-6. This compound is a critical building block in the synthesis of complex active pharmaceutical ingredients (APIs), offering a unique heterocyclic scaffold for medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents. Our supply is characterized by stringent quality control to ensure batch-to-batch consistency for demanding R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Contract Manufacturing (CMO): Used by contract development and manufacturing organizations (CDMOs) for the cGMP production of active pharmaceutical ingredients (APIs).
• Chemical Synthesis: Employed in academic and industrial laboratories for the construction of complex N- and O-containing heterocyclic systems.
• Process Development: Supports route scouting and process optimization for the efficient, scalable manufacture of target molecules.

Basic Information

Product Name	4-(Tetrahydro-Furan-3-Yloxy)-Pyridin-3-Ylamine
CAS No.	1342838-73-6
Molecular Formula	C9H12N2O2
Molecular Weight	180.20 g/mol
Synonyms	3-Amino-4-(3-furanyloxy)pyridine; 3-Pyridinamine, 4-[(tetrahydro-3-furanyl)oxy]-; 4-(Oxolan-3-yloxy)pyridin-3-amine; 4-(Tetrahydrofuran-3-yloxy)pyridin-3-amine; 4-(3-Furanyloxy)-3-pyridinamine; 1342838-73-6; 4-(Tetrahydrofuran-3-yloxy)pyridin-3-ylamine
EINECS	Contact for details

Quality Control

Our 4-(Tetrahydro-Furan-3-Yloxy)-Pyridin-3-Ylamine is manufactured under a quality management system and undergoes rigorous analytical testing. Each batch is supplied with a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant industry standards for pharmaceutical intermediates. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.