Description

6-Hydroxy-Nicotinic Acid tert-Butyl Ester is a high-purity, versatile chemical intermediate with a protected carboxylic acid group. This compound is critical for researchers and manufacturers requiring precise molecular building blocks for complex synthesis. It is primarily utilized in the pharmaceutical and agrochemical industries for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor and other small molecule therapeutic programs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its nicotinic acid derivative structure.
• Chemical Research: Acts as a protected precursor for further functionalization in organic and medicinal chemistry laboratories.
• Material Science: Employed in the synthesis of specialized ligands, catalysts, and functional polymers.
• API Development: Integral in the scale-up and process chemistry stages for Active Pharmaceutical Ingredient (API) manufacturing.

Basic Information

Product Name	6-Hydroxy-Nicotinic Acid tert-Butyl Ester
CAS No.	1342385-03-8
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	tert-Butyl 6-hydroxynicotinate; 6-Hydroxypyridine-3-carboxylic acid tert-butyl ester; 3-Pyridinecarboxylic acid, 6-hydroxy-, 1,1-dimethylethyl ester; Nicotinic acid, 6-hydroxy-, tert-butyl ester; 6-Hydroxy-3-pyridinecarboxylic acid tert-butyl ester; 6-Hydroxynicotinic acid t-butyl ester; t-Butyl 6-hydroxynicotinate
EINECS	Contact for details

Quality Control

Our 6-Hydroxy-Nicotinic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and commercial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.